Original Articles
Vol. 57 No. s4 (2005)
https://doi.org/10.4081/reumatismo.2005.4s.1

Are there differences among anti-TNFa biological drugs?

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Authors

G. Valesini
office@pagepress.org
, Italy.
Objective: To provide an analysis and a guide tool in using TNFa-antagonists in the current clinical practice. Methods: Review of the literature on the differences among the three TNFa-antagonists in terms of molecular structure, mechanism of action, pharmacokinetics, effects on the immune and neuroendocrine systems, and therapeutic indications. Results and conclusions: Unfortunately, results of direct comparison studies are lacking. One could obviate this problem by performing statistical-mathematical extrapolations, but there are very few and very small-sized published experimental evidences.

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1.
Are there differences among anti-TNFa biological drugs? Reumatismo [Internet]. 2005 Dec. 30 [cited 2026 Sep. 30];57(s4):1-2. Available from: https://www.reumatismo.org/reuma/article/view/reumatismo.2005.4s.1

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