Coexistence of axial spondyloarthritis and thromboangiitis obliterans in a young woman

  • G. Lopalco Interdisciplinary Department of Medicine, Rheumatology Unit, Policlinico of Bari, Italy.
  • F. Iannone Interdisciplinary Department of Medicine, Rheumatology Unit, Policlinico of Bari, Italy.
  • D. Rigante Institute of Pediatrics, Università Cattolica Sacro Cuore, Rome, Italy.
  • A. Vitale Research Center of Systemic Autoimmune and Autoinflammatory Diseases, Rheumatology Unit, Policlinico Le Scotte, University of Siena, Siena, Italy.
  • M.E. Mancini Interdisciplinary Department of Medicine, Diagnostic Radiology Unit, Policlinico of Bari, Italy.
  • M. Covelli Interdisciplinary Department of Medicine, Rheumatology Unit, Policlinico of Bari, Italy.
  • G. Lapadula Interdisciplinary Department of Medicine, Rheumatology Unit, Policlinico of Bari, Italy.
  • L. Cantarini | cantariniluca@hotmail.com Research Center of Systemic Autoimmune and Autoinflammatory Diseases, Rheumatology Unit, Policlinico Le Scotte, University of Siena, Siena, Italy.

Abstract

A peculiar coexistence of axial spondyloarthritis and ischemia of the feet and the fourth finger of the left hand in a young woman, who was a heavy smoker, is discussed in this report. This picture was considered within the context of thromboangiitis obliterans. Positivity of anti-nuclear antibodies and mild elevation of inflammatory parameters were noted. Computed tomography angiograms of upper and lower limbs showed luminal narrowing and occlusion of the left humeral, left anterior/posterior tibial and right anterior tibial arteries. Daily iloprost perfusions were started, and smoking cessation was strongly recommended. Coldness and rest pain in the distal extremities improved within a few weeks. The possibility that spondyloarthritis might precede the clinical picture of thromboangiitis obliterans should be considered in heavy smokers.

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Published
2015-06-30
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Section
Case Reports
Keywords:
Thromboangiitis obliterans, Axial spondyloarthritis.
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How to Cite
Lopalco, G., Iannone, F., Rigante, D., Vitale, A., Mancini, M., Covelli, M., Lapadula, G., & Cantarini, L. (2015). Coexistence of axial spondyloarthritis and thromboangiitis obliterans in a young woman. Reumatismo, 67(1), 17-20. https://doi.org/10.4081/reumatismo.2015.810