Case Reports
6 November 2014
Vol. 66 No. 3 (2014)
https://doi.org/10.4081/reumatismo.2014.750

Superior oblique tendon (Brown’s) syndrome as the presenting finding in childhood onset HLA-B27-related enthesitis and juvenile idiopathic oligoarticular arthritis

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Brown’s syndrome, Spondyloarthropathy, HLA-B27, Enthesitis, Juvenile arthritis.
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Authors

C. Pham
Case Western Reserve University, Cleveland, OH, United States.
V. Utz
Cole Eye Institute, Cleveland Clinic, Cleveland, OH, United States.
A. Marcotty
Cole Eye Institute, Cleveland Clinic, Cleveland, OH, United States.
A. Zeft
zefta@ccf.org
Division of Rheumatology, Pediatric Institute, Cleveland Clinic, Cleveland, OH, United States.
P. Rychwalski
Cole Eye Institute, Cleveland Clinic, Cleveland, OH, United States.
We report two patients who presented with Brown’s syndrome. The first is a 7-year-old boy who at the time of his diagnosis was also found to have enthesitis and HLA-B27 positivity. The second patient was diagnosed with bilateral Brown’s syndrome at 13 months of age. At age 7 she developed a persistent oligoarticular arthritis and unilateral anterior iritis consistent with the oligoarticular Juvenile Idiopatic Arthritis (JIA) phenotype. These cases highlight ophthalmologic findings and diagnostic considerations with respect to Brown’s syndrome and associated childhood onset rheumatologic disease.

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Superior oblique tendon (Brown’s) syndrome as the presenting finding in childhood onset HLA-B27-related enthesitis and juvenile idiopathic oligoarticular arthritis. (2014). Reumatismo, 66(3), 240-244. https://doi.org/10.4081/reumatismo.2014.750

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