Reviews
Vol. 55 No. 3 (2003)
https://doi.org/10.4081/reumatismo.2003.147

Drug-induced lupus erythematosus

Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
7745
Views
19214
Downloads

Authors

F. Atzeni
office@pagepress.org
, Italy.
M.G. Marrazza
, Italy.
P. Sarzi-Puttini
, Italy.
M. Carrabba
, Italy.
Drug-induced lupus is a syndrome which share symptoms and laboratory characteristics with the idiopathic systemic lupus erythematosus (SLE). The list of medications implicated as etiologic agents in drug-induced lupus continues to grow. The terms used for this condition are lupus-like syndrome, drug-induced lupus erythematosus (DILE) and drug related lupus. More than 80 drugs have been associated with DILE. The first case of DILE was reported in 1945 and associated with sulfadiazin. In 1953 it was reported that DILE was related to the use of hydralazine. Drugs responsible for the development of DILE can divided into three groups, but the list of these drugs is quite long because new drugs are included yearly in the list. The syndrome is characterised by arthralgia, myalgia, pleurisy, rash and fever in association with antinuclear antibodies in the serum. Recognition of DILE is important because it usually reverts within a few weeks after stopping the drug.

Downloads

Download data is not yet available.

How to Cite



1.
Drug-induced lupus erythematosus. Reumatismo [Internet]. 2003 Sep. 30 [cited 2026 Sep. 3];55(3):147-54. Available from: https://www.reumatismo.org/reuma/article/view/reumatismo.2003.147

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.