Demyelinating syndrome in SLE: review of different disease subtypes and report of a case series
AbstractDemyelinating syndrome (DS) is a rare manifestation of systemic lupus erythematosus (SLE) (1%) with high clinical heterogeneity and potentially severe prognosis. It can represent a diagnostic and therapeutic challenge for clinicians. A recent study described 5 different patterns of demyelinating disease presentation, characterised by specific clinical, laboratory and brain and spine magnetic resonance imaging abnormalities: 1) neuromyelitis optica; 2) neuromyelitis optica spectrum disorders; 3) DS prevalently involving the brain; 4) DS prevalently involving the brainstem; 5) clinically isolated syndrome. In this review we briefly discuss typical characteristics of each DS presentation in SLE and we describe 5 illustrative clinical cases, one for each subset of DS, considering both diagnostic and therapeutic options.
- Abstract views: 1470
- PDF: 667
Copyright (c) 2017 E. Chessa, M. Piga, A. Floris, A. Mathieu, A. Cauli
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.