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Assessment of treatment effects on digital ulcer and blood perfusion by laser speckle contrast analysis in a patient affected by systemic sclerosis

B. Ruaro, S. Paolino, C. Pizzorni, M. Cutolo, A. Sulli
  • B. Ruaro
    Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Ospedale Policlinico San Martino, Genoa, Italy | barbara.ruaro@yahoo.it
  • S. Paolino
    Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Ospedale Policlinico San Martino, Genoa, Italy
  • C. Pizzorni
    Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Ospedale Policlinico San Martino, Genoa, Italy
  • M. Cutolo
    Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Ospedale Policlinico San Martino, Genoa, Italy
  • A. Sulli
    Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Ospedale Policlinico San Martino, Genoa, Italy

Abstract

Laser speckle contrast analysis (LASCA) is a good tool to evaluate the variation in peripheral blood perfusion during long-term follow-up and is able to safely monitor digital ulcer evolution in scleroderma patients. It evaluates blood perfusion in different areas within the skin lesions and surrounding them during standard treatment.

Keywords

Systemic sclerosis, LASCA, blood perfusion.

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Submitted: 2017-03-20 20:04:51
Published: 2017-09-21 12:06:27
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Copyright (c) 2017 B. Ruaro, S. Paolino, C. Pizzorni, M. Cutolo, A. Sulli

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